Pharmaceutical Research Partners
PIN provides pharmaceutical partners with direct access to a verified, credentialled network of pain medicine specialists — enabling robust real-world evidence studies, pharmacovigilance programmes, and digital health tool validation across multiple countries.
Partnership Models
Four primary models for pharmaceutical engagement with the PIN physician network.
Real-World Evidence Studies
PIN member sites provide access to prospective patient cohorts and retrospective registries for post-market surveillance and comparative effectiveness research in pain medicine.
- Multi-country patient registry design and data collection
- Comparative effectiveness: drug vs. interventional approaches
- Long-term outcomes tracking across diverse patient populations
- Asia-Pacific, European, and Latin American cohort access
Pharmacovigilance & Safety
PIN's physician network supports ongoing safety monitoring of pain medications across the full therapeutic lifecycle — from clinical practice feedback to structured adverse event reporting.
- Structured adverse event collection from specialist clinicians
- Drug interaction and tolerance monitoring
- Opioid stewardship and prescribing practice surveillance
- Regulatory submission support and medical writing
Digital Health & AI Tool Validation
PIN members have co-authored prospective clinical trials validating AI-powered digital pain management tools, with expertise in digital endpoint design and patient-reported outcome collection.
- Multi-centre clinical trials for digital therapeutics
- PRO and quality-of-life endpoint validation
- AI decision support tool benchmarking
- Cost-effectiveness modelling for digital interventions
Device & Interventional Research
PIN's neuromodulation and interventional specialists support device companies with clinical validation, post-market studies, and investigator-initiated research for stimulation, radiofrequency, and regenerative devices.
- Spinal cord stimulation and PNS device outcomes
- Radiofrequency ablation comparative effectiveness
- Regenerative and prolotherapy product validation
- Investigator-initiated device studies
Research Highlights
Examples of pharmaceutical-relevant research conducted by PIN network members.
Multi-Country Tramadol/Dexketoprofen Registry (REKOVER)
A prospective real-world registry studying the effectiveness and safety of fixed-dose tramadol/dexketoprofen in acute pain across multiple Asian countries, spanning 3 BMJ Open publications.
AI-Powered Chronic Pain Self-Management Tool — Prospective Multi-Centre Trial
A prospective multi-centre clinical trial demonstrating quality-of-life gains and cost savings from an AI-powered digital pain management tool, published in Pain Medicine.
Evidence & Gap Map for Ozone as Integrative Medicine
A systematic evidence and gap map evaluating ozone therapy across pain indications, providing the evidence base for future ozone therapeutic product development and labelling claims.
MrgprX1 Positive Allosteric Modulator for Neuropathic Pain
Translational research published in Science Translational Medicine demonstrating an orally bioavailable novel compound alleviating neuropathic pain in humanised mice — a potential pipeline candidate.
Gabapentin Meta-Analysis: 440-Citation Landmark Study
A widely-cited meta-analysis on the analgesic effects of perioperative gabapentin, influencing prescribing guidelines across North America and cited in over 440 subsequent papers.
Cannabinoid Receptor Analgesia — Nature Neuroscience
Foundational research on peripheral CB1 receptor-mediated analgesia providing mechanistic rationale for peripherally restricted cannabinoid analgesic drug development.
Partnership Process
How a pharmaceutical collaboration with PIN comes together — from initial enquiry to active study.
Discovery Call
Discuss your research objective, therapeutic area, geography, and timeline with the PIN partnerships team.
Investigator Matching
We identify the best-fit PIN member physicians by specialty, site capability, patient volume, and location.
Protocol & Governance
Joint protocol design, IRB submission support, data governance agreements, and compliance review.
Active Study
Recruitment, data collection via PIN's platform, ongoing monitoring, and publication support.
Compliance & Data Standards
All pharmaceutical partnerships operate within PIN's established regulatory and data governance framework.
HIPAA Compliant
All patient data handled under US HIPAA standards with BAA agreements for pharmaceutical partners.
GDPR Ready
European data processing agreements and consent frameworks in place for EU/EEA site data.
FHIR R4
FHIR-compliant data export for seamless integration with sponsor data management systems.
Explore a partnership
Whether you need a multi-country RWE registry, a pharmacovigilance programme, or an investigator for a device study, PIN's physician network can be your research foundation.
Contact the Partnerships Team View Member Research