Pre-Seed Round · Global Investor Briefing

The global intelligence OS for pain medicine –
connecting 14 countries through one unified platform

PIN is not a registry. It is a data-powered, physician-governed operating system for the world's most underserved chronic disease · enhanced with a pharmacovigilance layer that makes it the only real-world platform where clinical outcomes and drug safety data live in the same longitudinal dataset. Regulators, payers, and pharma sponsors have been waiting for this for decades.

Market Opportunity
$624B
Chronic LBP Economic Burden
Total U.S. TAM
$40B
Direct Annual Spend
PIN's beachhead
12%
Part B Revenue at Risk
By 2031, under CMS ASM
$260K
CMS Exposure at Risk
Up to $220K net savings
Clinical Network Advantage · Global Reach
1,000+ Physicians
AAPM Partnership Path
Warm specialty-society access into the pain practices most exposed to CMS Ambulatory Specialty Model pressure. The AAPM launch path gives PainOS a trusted channel before mandatory compliance reshapes the market.
Up to 14 States
Strategic Clinic Pipeline
National Pain and Spine discussions create a near-term multi-state expansion path. One strategic relationship can move PainOS from specialty-society channel to clinic-group deployment.
14 Countries
Pain Innovation Network Footprint
The Pain Innovation Network gives PainOS a practical international expansion option after U.S. ASM adoption, without diluting the immediate U.S. regulatory wedge.
1 Category Wedge
Pain as the First Specialty Risk Domain
Start where regulation forces adoption. Expand where outcomes infrastructure, audit-ready care coordination, and specialty-practice risk management become unavoidable.
Revenue Model · 7 Streams
Revenue StreamModelYr 1Yr 2Yr 3Status
ASM Implementation Setup
White-glove clinic onboarding
$10K-$12K/clinic$1.0M-$1.2M$2.5M-$3.6M$7.5M-$12MPrimary
Patient Follow-Up PMPM
Between-visit monitoring + app engagement
$8-$15 PMPM$200K-$450K$1.2M-$2.7M$2.4M-$5.4MRamp
Platform Subscriptions
Clinic software license + ASM workflows
Annual clinic license$100K-$240K$300K-$720K$900K-$2.4MPrimary
Premium Memberships + CME
AAPM/PIN education and member tools
$200-$300/yr individual$80K$220K$600KLive
Research Registry Access
De-identified data for academia/industry
Per-study fee$80K$350K$1.5MLive
PASS / PMS Study Fees
Post-authorization safety studies
$50K-$150K/study-$400K$1.6MPhase 2
PV + Payer AI Licensing
Signal detection, payer analytics, opioid risk API
SaaS + API-$440K$3.2MPhase 2
Funding Roadmap
Now → Month 6
Pre-Seed / ASM Launch · US
  • Co-branded AAPM distribution path
  • 1,000+ MD channel; 100-clinic launch pool; 10-25 initial conversions
  • $10K-$12K white-glove implementation per clinic/location
  • $8-$15 PMPM patient follow-up economics
  • $1M-$1.2M gross implementation upside if 100 clinics convert
$750K Pre-Seed
Month 6 → 18
Scale / Seed · U.S. Expansion
  • Grow from 100-clinic upside to 250-300 clinic pipeline
  • $2.5M-$3.6M setup sales potential at $10K-$12K/clinic
  • $8-$15 PMPM follow-up expands recurring revenue base
  • PV SaaS + PASS studies remain secondary expansion streams
$3M Seed
Month 18 → 36
Expand / Series A · Platform Scale
  • 750-1,000 clinic scale target across U.S. and global channels
  • $7.5M-$12M setup sales potential before recurring PMPM
  • Full PV platform, payer analytics, and 8+ pharma clients
  • Government / EMA / FDA / Health Canada contract pathway
$12M Series A
Why Invest Now · Market Validation

Pain Medicine is at an Inflection Point

CMS's Ambulatory Specialty Model turns pain physicians into accountable-risk operators starting Jan 2027, creating an urgent buyer inside a $624B total burden / $40B direct-spend beachhead for the intelligence platform that gets practices audit-ready.

  • CMS ASM holds individual physicians — not hospitals — accountable for episode cost and outcomes
  • Any group managing 20+ Medicare LBP episodes/yr in a launch market must comply — not optional
  • Specialists drive most CMS spending growth — pain is the pilot for MSK, cancer, and mental health next
  • Payment risk escalates from 9% to 12% of Part B revenue between 2027 and 2031

First-Mover Advantage

PIN is the only platform designed specifically for pain medicine with built-in pharmacovigilance, multi-site research capabilities, and payer analytics in a single integrated OS.

14
Countries
7
Revenue Streams
1,000+
Physicians
$260K
Exposure at Risk
Pre-Seed Investment Opportunity

Join the Global Intelligence Revolution in Pain Medicine

PIN is positioned to become the standard global data infrastructure for pain medicine—connecting 14 countries, a 1,000+ physician AAPM-enabled channel, and CMS compliance-grade risk data in a single, unified platform. The window for early participation is closing.

Funding Round
$750K Pre-Seed
Pre-Money Valuation
$8.5M
Use of Funds
ASM Launch

For investor inquiries, contact:

investors@paininnovation.net